Publications

Journal Articles

59. Aguilar, S., Moreira, D.C., Lourenço, A.L., Wilke, N., Crosio, M., Vasconcelos, A., Barbosa, E.A., Iseke Bispo, E.C., Saldanha-Araujo, F., Ramada, M., Escobar, F.M., Torres, C.V., Leite, J.R.S.A., Marani, M.M. 2025. Enhancing Antimicrobial Peptides from Frog Skin: A Rational Approach. Biomolecules, 15, 449. DOI. 

58. Queiroz, J., Figueredo, A., Sá, B., Moreira, D.C., Nunes, J., Eaton, P., Leite, J.R. and Vasconcelos, A. 2025. Antioxidant Activity and Cytotoxicity of Baru Nut Oil (Dipteryx alata Vogel) Nanoemulsion in Human Cells. Applied Nano, 6, 3. DOI.

57. Nogueira,  A., Brango-Vanegas, J., Vasconcelos, A.G.,  Coleone, A.P., Barbosa, E.A., Moreira, D.C.,  da Silva, M.G., Cabral, W.F., Dias, J.N. . et al.  2025. Novel tryptophyllin peptides from Physalaemus centralis inhibit oxidative stress-induced endothelial dysfunction in rat aorta preparation. Toxicon, 255, 108234. DOI.

56. Siqueira, B.S., Urritia, M.A.D., Ceglarek, V.M., Moreira, D.C., Kuzniewski, F.T.B., Leite, J.R.S.A. and Grassioli, S. 2025. A novel bombesin-related peptide modulates glucose tolerance and insulin secretion in non-obese and hypothalamic-obese rats. Toxicon, 255, 108230. DOI.

Journal Articles

55. Moreira, F.D., Reis, C.E.G., Gallassi, A.D., Moreira, D.C. and Welker, A.F. 2024. Suppression of the postprandial hyperglycemia in patients with type 2 diabetes by a raw medicinal herb powder is weakened when consumed in ordinary hard gelatin capsules: A randomized crossover clinical trial. PLOS ONE, 19, e0311501. DOI. Citations.

54. Bars-Closel, M., Capparelli, M.V., Conradie, S.R., Diele-Viegas, L.M., Donaldson, A.C., Kosmala, G.K., Madelaire, C.B., Mello, D.M.D., Majelantle, T.L. et al. 2024. The challenges, opportunities and future of comparative physiology in the Global South: Perspectives of early career researchers. Journal of Experimental Biology, 227,  jeb247888, DOI. Citations.

⭐ 53. Moreira, D.C. and Hermes-Lima, M. 2024. Dynamics of redox metabolism during complete metamorphosis of insects: Insights from the sunflower caterpillar Chlosyne lacinia (Lepidoptera). Antioxidants, 13, 959. DOI. 

52. Cancelarich, L.N., Arrulo, M., Gugliotti, S.T., Barbosa, E.A., Moreira, D.C., Basso N.G., Pérez, L.O., de la Torre, B.G., Albericio, F. et al. 2024. First bioprospecting study of skin host-defense peptides in Odontophrynus americanus. Journal of Natural Products, 87, 1714-1724. DOI.

51. Moreira, D.C., Carvalho, D.N.,  Santos, E., Relvas, J.B., Neves, M.A.D. and Pinto, I.M. 2024. Multi-parametric decision system for analytical performance assessment of electrochemical (bio)sensors. Advanced Materials Technologies, 2301464. DOI. Citations.

50. Silva, G.R., Miranda, L.T.G., Silva, S.A.C.A., Andrade, L.R., Souza, N.C., Sá, B.S., Santana, E.R., Vasconcelos, A.G., Moreira, D.C. et al. 2024. Toxicity and teratogenic potential of piplartine from Piper tuberculatum Jacq. during embryonic development in mice (Mus musculus). Drugs and Drug Candidates, 3, 353-367. DOI. Citations.

49. Giraud-Biloud, M., Moreira, D.C., Minari, M.,  Andreyeva, A., Campos, E.G., Carvajalino-Fernández, J.M., Istomina, A., Michaelidis, B., Niu, C. et al. 2024. Evidence supporting the 'Preparation for Oxidative Stress' (POS) strategy in animals in their natural environment. Comparative Biochemistry and Physiology A, 293, 111626. DOI. Citations.

48. Melo-Fonseca, F., Gasik, M., Cruz, A., Moreira, D.C., Silva, F.S., Miranda, G. and Pinto, I.M. 2024. Engineering a hybrid Ti6Al4V-based system for responsive and consistent osteogenesis. ACS Omega, 9, 8985–8994. DOI. Citations.

Book chapter

47. Moreira, D.C., Batagin-Neto, A and Leite, J.R.S.A. 2024. Frog-derived neuroprotective peptides. In M.R. de Oliveira (Ed.), Natural Molecules in Neuroprotection and Neurotoxicity. Elsevier. Link. DOI. Citations.

Journal Articles

46. Moreira, D.C., Zenteno-Savín, T. and Hermes-Lima, M. 2023. Redox metabolism in ecophysiology and evolution. Antioxidants, 12, 1769. DOI. Citations.

45. Moreira, D.C.  2023. RGBradford: Protein quantitation with a smartphone camera. Journal of Visualized Experiments, 199, e65547. DOI.

44. Silva-Carvalho, A.E., Oliveira, N.N., Machado, J.V.L., Moreira, D.C., Brand, G.D., Leite, J.R.S.A., Placido, A, Eaton, P. and Saldanha-Araujo, F. 2023. The peptide salamandrin-I modulates components involved in pyroptosis and induces cell death in human leukemia cell line HL-60. Pharmaceutics, 15, 1864. DOI. Citations.

43. Paula, J.R., Wang, X., Xu, C. and Moreira, D.C. 2023. Editorial: The defense responses of aquatic animals to the environment. Frontiers in Physiology, 14, 1231014. DOI.

42. Ferreira-Cravo, M.*, Moreira, D.C.* and Hermes-Lima, M. 2023. Glutathione depletion disrupts redox homeostasis in an anoxia-tolerant invertebrate. Antioxidants, 12, 1197. DOI. Citations. *These authors contributed equally.

41. Moreira, D.C., Sabino, M.A.C.T., Minari, M., Kuzniewski, F.T.B., Angelini, R., Hermes-Lima, M. 2023. The role of solar radiation and tidal emersion on oxidative stress and glutathione synthesis in mussels exposed to air. PeerJ, 11, e15345. DOI. Citations.

40. Farias, J.P.,  Barros, A.L.A.N., Araújo-Nobre, A.R., Sobrinho-Júnior, E.P.C.,  Alves, M.M.M., Carvalho, F.A.A., Rodrigues, K.A.F., Andrade, I., Silva-Filho, F.A.,  et al. 2023. Influence of plant age on chemical composition, antimicrobial activity and cytotoxicity of Varronia curassavica Jacq. essential oil produced on an industrial scale. Agriculture, 13, 373. DOI. Citations.

39. Moreira, D.C., Campos, E.G., Giraud-Billoud, M., Storey, K.B. and Hermes-Lima, M. 2023. Commentary: On the merit of an early contributor of the “Preparation for Oxidative Stress” (POS) theory. Comparative Biochemistry and Physiology A, 276, 111341. DOI. Citations.

38. Aguilar, S., Brunetti, A.E., Garay, A.V., Santos, L.C., Perez, L.O.,  Moreira, D.C., Cancelarich, L., Barbosa, E.A., Basso, N.G. et al. 2023. Structure and function of cationic hylin bioactive peptides from the tree frog Boana pulchella in interaction with lipid membranes.  Peptides, 159, 170900. DOI. Citations.

Journal Articles

37. Dematei A., Costa, S.R., Moreira, D.C., Barbosa, E., Albuquerque, L.F.F., Vasconcelos, A.G., Nascimento, T., Silva, P.C., Silva-Carvalho, A.E. et al. 2022. Antioxidant and neuroprotective effects of the first tryptophyllin found in snake venom (Bothrops moojeni). Journal of Natural Products, 85, 2695–2705. DOI. Citations.

36. Gisbert, E.,  Moreira, D.C., Lu, K.L. and Mozanzadeh, M.T. 2022. Editorial: Rising stars in aquatic physiology: 2022. Frontiers in Physiology,  13, 1081961. DOI.

⭐ 35.  Moreira, D.C. 2022. RGBradford: Accurate measurement of protein concentration using a smartphone camera and the blue to green intensity ratio. Analytical Biochemistry, 655, 114839. DOI. Citations.

34. Moreira, D.C., Wang, Y., López-Martínez, G. and Hermes-Lima, M. 2022. Editorial: Redox metabolism in environmental and ecological physiology of animals. Frontiers in Physiology, 13, 904746. DOI. 

33. Plácido, A., Amaral, C.P., Teixeira, C., Nogueira, A., Brango-Venegas, J., Barbosa, E.A., Moreira, D.C., Silva-Carvalho, A.E., Silva, M.A. et al. 2022. Neuroprotective effects on microglia and insights into the structure–activity relationship of an antioxidant peptide isolated from Pelophylax perezi. Journal of Cellular and Molecular Medicine, 26, 2793–2807. DOI. Citations.

32.  Santos, B.W.L., Moreira, D.C., Borges, T.K.S. and Caldas, E.D. 2022. Components of Banisteriopsis caapi, a plant used in the preparation of  the psychoactive ayahuasca, induce anti-inflammatory effects in microglial  cells. Molecules, 27, 2500. DOI. Citations.

31. de Sousa, N.A., Marani, M.M., Lopes, A.L.F., Silva, E.M., Barbosa, E.A., Vasconcelos, A.G., Kuzniewski, F.T.B., Lustosa, S.S., Gomes, K.P. et al. 2022. BR-bombesin: A novel bombesin-related peptide from the skin secretion of the Chaco tree frog (Boana raniceps) with physiological gastric effects. Amino Acids, 54, 733–747. DOI. Citations.

30. Sahin, C., Magomedova, L., Ferreira, T.A.M., Liu, J., Tiefenbach, J., Alves, P.S.,  Queiroz, F.J.G., Oliveira, A.S., Bhattacharyya, M. et al. 2022. Phenolic lipids derived from cashew nut shell liquid to treat metabolic diseases. Journal Medicinal Chemistry, 65, 1961–1978. DOI. Citations.

29.  Barros, A.L.A.N., Hamed, A., Marani, M., Moreira, D.C., Eaton, P., Plácido, A., Kato, M.J. and Leite, J.R.S.A. 2022. The arsenal of bioactive molecules in the skin secretion of urodele amphibians.  Frontiers in Pharmacology, 12, 810821. DOI. Citations.

 Journal Articles

⭐ 28.  Moreira, D.C., Carvajalino-Fernández, J.M., Navas, C.A., de Carvalho, J.E. and Hermes-Lima, M. 2021. Metabolic and redox biomarkers in skeletal muscle underlie physiological adaptations of two estivating anuran species in a South American semi-arid environment. Frontiers in Physiology, 12, 769833. DOI. Citations.

27. Barbosa, E.A., Plácido A., Moreira, D.C., Albuquerque, L., Dematei, A., Silva-Carvalho, A.E., Cabral, W.F.,  Báo, S.N., Saldanha-Araújo, F. et al. 2021. The peptide secreted at the water to land transition in a model amphibian has antioxidant effects. Proceedings of the Royal Society B: Biological Sciences, 288, 20211531. DOI. Citations.

26. Vasconcelos, A.G., Barros, A.L.A.N., Cabral, W.F., Moreira, D.C., Silva, I.G.M., Silva-Carvalho, A., Almeida, M.P., Albuquerque, L.F.F., dos Santos, R.C. et al. 2021. Promising self-emulsifying drug delivery system loaded with lycopene from red guava (Psidium guajava L.): in vivo toxicity, biodistribution and cytotoxicity on DU-145 prostate cancer cells. Cancer Nanotechnology, 12, 30. DOI. Citations.

25. Dematei, A., Nunes, J.B., Moreira, D.C., Jesus, J.A., Laurenti, M.D., Mengarda, A.C.A., Vieira, M.S., Amaral, C.P., Domingues, M.M. et al. 2021. Mechanistic insights into the leishmanicidal and bactericidal activities of batroxicidin, a cathelicidin-related peptide from a South American viper (Bothrops atrox). Journal of Natural Products,  84, 1787–1798. DOI. Citations.

24. Moreira, D.C., Sabino, M.A.C.T., Kuzniewski, F.T.B., Furtado-Filho, O.V., Carvajalino-Fernández, J.M., Angelini, R., Freire, C.A. and Hermes-Lima, M. 2021. Redox metabolism in mussels (Brachidontes solisianus) under the influence of tides in a rocky beach in Southern Brazil. Estuarine, Coastal and Shelf Science, 258, 107424. DOI. Citations.

⭐ 23. Moreira, D.C., Paula, D.P. and Hermes-Lima, M. 2021. Changes in metabolism and antioxidant systems during tropical diapause in the sunflower caterpillar Chlosyne lacinia (Lepidoptera: Nymphalidae). Insect Biochemistry and Molecular Biology, 134, 103581. DOI. Citations.

Journal Articles

22. Almeida, R.M.V.R., Borges, L.F.F., Moreira, D.C. and Hermes-Lima, M. 2020. New metrics for cross-country comparison of scientific impact. Frontiers in Research Metrics and Analytics, 5, 594891. DOI. Citations.

21. Caetano-Silva, M.E., Simabuco, F.M., Bezerra, R.M.N., Silva, D.C., Barbosa, E.A., Moreira, D.C., Brand, G.D., Leite, J.R.S.A. and Pacheco, M.T.B. 2020. Isolation and sequencing of Cu-, Fe-, and Zn-binding whey peptides for potential neuroprotective applications as multitargeted compounds. Journal of Agricultural and Food Chemistry, 68, 12433–12443. DOI.  Citations.

20. Kückelhaus, S.A.S., de Aquino, D.S., Borges, T.K., Moreira, D.C., Leite, L.M., Muniz-Junqueira, M.I., Kückelhaus, C.S., Romero, G.A.S., Prates, M.V. et al. 2020. Phylloseptin-1 is leishmanicidal for amastigotes of Leishmania amazonensis inside infected macrophages. International Journal of Environmental Research and Public Health, 17(13), 4856. DOI. Citations. 

⭐ 19. Moreira, D.C., Carvajalino-Fernández, J.M., Silva, W.P., Kuzniewski, F., Navas, C.A., Carvalho, J.E. and Hermes-Lima, M. 2020. Preparation for oxidative stress in Proceratophrys cristiceps (Anura, Odontophrynidae) naturally estivating in the Brazilian Caatinga. Science of the Total Environment, 723, 137957. DOI. Citations.

18. Plácido, A., Bueno, J., Barbosa, E.A., Moreira, D.C., Dias, J.N., Cabral, W.F., Albuquerque, P., Bessa, L.J., Freitas, J. et al. 2020. The antioxidant peptide salamandrin-I: first bioactive peptide identified from skin secretion of salamandra genus (Salamandra salamandra). Biomolecules, 10(4), 512. DOI. Citations.

17. Cancelarich, N.L., Wilke, N., Fanani, M.L., Moreira, D.C., Pérez, L.O., Barbosa, E.A., Plácido, A., Socodato, R., Portugal, C.C. et al. 2020. Somuncurins: bioactive peptides from the skin of the endangered endemic Patagonian frog Pleurodema somuncurense. Journal of Natural Products, 83(4), 972–984. DOI. Citations.

16. Geihs, M.A.*, Moreira, D.C.*, López-Martínez, G., Minari, M., Ferreira-Cravo, M., Carvajalino-Fernández, J.M. and Hermes-Lima, M. 2020. Ultraviolet radiation triggers “preparation for oxidative  stress” antioxidant response in animals: Similarities and interplay with other stressors. Comparative Biochemistry and Physiology A, 239, 110585. DOI. Citations. *These authors contributed equally.

Journal Articles

15. Giraud-Billoud, M., Rivera-Ingraham, G.A., Moreira, D.C., Burmester, T., Castro-Vaquez, A., Carvajalino-Fernández, J.M., Dafre, A., Niu, C., Tremblay, N. et al. 2019. Twenty years of the 'Preparation for Oxidative Stress' (POS) theory: Ecophysiological advantages and molecular strategies. Comparative Biochemistry and Physiology A, 234, 36–49. DOI. Citations.

Journal Articles

14. Oliveira, M.F., Geihs, M.A., Moreira, D.C. and Hermes-Lima, M. 2018. Is “Preparation for Oxidative Stress” a case of physiological conditioning hormesis? Frontiers in Physiology, 9, 945. DOI. Citations. Corrigendum.

13. Dalvi, L.T., Moreira, D.C., Alonso, A., de Avellar, I.G.J. and Hermes-Lima, M. 2018. Antioxidant activity and mechanism of commercial Rama Forte persimmon fruits (Diospyros kaki). PeerJ, 6, e5223. DOI. Citations.

12. Campelo, Y.D.M., Ombredane, A., Vasconcelos, A.G., Albuquerque, L.F.F., Moreira, D.C., Placido, A., Rocha, J.A., Fokoue, H.H., Yamaguchi, L.F. et al. 2018. Structure-activity relationship of piplartine and synthetic analogues against Schistosoma mansoni and cytotoxicity to mammalian cells. International Journal of Molecular Sciences, 19(6), 1802. DOI.  Citations.

11. Moreira, D.C.*, Welker, A.F.*, Campos, E.G., de Souza, S.C.R. and Hermes-Lima, M. 2018. Subtropical hibernation in juvenile tegu lizards (Salvator merianae): insights from intestine redox dynamics. Scientific Reports, 8, 9368. DOI. Citations. *These authors contributed equally.

10. Barbosa, E., Oliveira, A., Plácido, A., Socodato, R., Portugal, C.C., Mafud, A.C., Ombredane, A.S., Moreira, D.C., Vale, N. et al. 2018. Structure and function of a novel antioxidant peptide from the skin of Tropical frogs. Free Radical Biology and Medicine, 115, 68–79. DOI. Citations.

Journal Articles

⭐ 9. Moreira, D.C., Oliveira, M.F., Liz-Guimarães, L., Diniz-Rojas, N., Campos, E.G. and Hermes-Lima, M. 2017. Current trends and research challenges regarding “preparation for oxidative stress.” Frontiers in Physiology, 8, 702. DOI. Citations.

8. Rolim, E.C.*, Oliveira, J.M.*, Dalvi, L.T.*, Moreira, D.C.*, Caldas, N.G., Lobo, F.F., Polli, D.A., Campos, E.G. and Hermes-Lima, M. 2017. Blog construction as an effective tool in biochemistry active learning. Biochemistry and Molecular Biology Education, 45(3), 205–215. DOI. Citations. *These authors contributed equally.

7. Dalvi, L.T., Moreira, D.C., Andrade Jr., R., Ginani, J., Alonso, A. and Hermes-Lima, M. 2017. Ellagic acid inhibits iron-mediated free radical formation. Spectrochimica Acta A, 173, 910–917. DOI. Citations.

Journal Articles

⭐ 6. Moreira, D.C., Venancio, L.P.R., Sabino, M.A.C.T. and Hermes-Lima, M. 2016. How widespread is preparation for oxidative stress in the animal kingdom? Comparative Biochemistry and Physiology A, 200, 64–78. DOI. Citations.

5. Welker, A.F., Moreira, D.C. and Hermes-Lima, M. 2016. Roles of catalase and glutathione peroxidase in the tolerance of a pulmonate gastropod to anoxia and reoxygenation. Journal of Comparative Physiology B, 186(5), 553–568. DOI. Citations.

Journal Article

⭐ 4. Hermes-Lima, M.*, Moreira, D.C.*, Rivera-Ingraham, G.A., Giraud-Billoud, M., Genaro-Mattos, T.C. and Campos, E.G. 2015. Preparation for oxidative stress under hypoxia and metabolic depression: Revisiting the proposal two decades later. Free Radical Biology and Medicine, 89, 1122–1143. DOI. Citations. *These authors contributed equally.

No publications this year :(

Journal Article

3. Welker, A.F., Moreira, D.C., Campos, E.G. and Hermes-Lima, M. 2013. Role of redox metabolism for adaptation of aquatic animals to drastic changes in oxygen availability. Comparative Biochemistry and Physiology A, 165(4), 384–404. DOI. Citations.

Journal Article

2. Hermes-Lima, M., Carreiro, C., Moreira, D.C., Polcheira, C., Machado, D.P. and Campos, E.G. 2012. Glutathione status and antioxidant enzymes in a crocodilian species from the swamps of the Brazilian Pantanal. Comparative Biochemistry and Physiology A, 163(2), 189–198. DOI. Citations.

Book Chapter

1. Moreira, D.C., Paula, D.P. and Hermes-Lima, M. 2012. Redox metabolism during tropical diapause in a Lepidoptera larva. In: Living in a Seasonal World (Ruf, T., Bieber, C., Arnold, W. and Millesi, E., eds.). Springer, Berlin, Heidelberg, Ch. 35, pp. 399–409. DOI. Citations.